食品添加劑在特殊人群中的安全性評估
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Safety Assessment of Food Additives in Special Populations
WEI Pingxia
（Lanzhou Petrochemical University of Vocational Technology， Lanzhou 73o207， China）
Abstract： This paper evaluates the health risks of aspartame in pregnant women， infants，phenylketonuria （PKU） patients and patients with chronic diseases，analyzes the diferences inthe methodologies ofcarcinogenicity assessment in international institutions，proposes a hierarchical threshold management system based onmetabolic Vulnerability，and suggests strengthening waring signs，accurate monitoring and dynamic risk communication.This studycan provide a scientific basis for the revision offood additive safety standards for special populations，and then promote a diferentiated risk management framework， which has important practical value for improving the global regulatory system and protecting the health of sensitive groups.
Keywords： food additives; special population; safety assessment
2023年7月，世界衛(wèi)生組織（WorldHealthOrganization，WHO）下屬國際癌癥研究機構(gòu)（International AgencyforResearchon Cancer，IARC）將阿斯巴甜（Aspartame）列為2B類可能致癌物（對人類致癌性證據(jù)有限），與其在180多個國家、6000余種食品飲料中的廣泛使用形成鮮明對比。（剩余4952字）