雙水平無創(chuàng)呼吸機對肺源性心臟病合并睡眠呼吸暫停慢性心力衰竭患者的影響

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AbstractObjective：Toevaluatethemedicalvalueofbi-levelnon-invasiveventilationinthetreatmentofwithchronicheart failurecomplicatedwith pulmonary heartdiseaseandsleepapnea.Methods：Atotalof6O patients with chronic heartfailure with thecomplicationofpulmonaryheartdiseaseandsleepapnea whoadmited inthehospitalfromJanuary2O22toDecember2023 were enroledand evenly divided intoacontrol groupandanobservation group byrandom numbertable.Thecontrolgroup receivedroutinetreatment，hiletheobservationgroupaditioalhadbi-levelnon-invasiveventilationtreatmentTheresultsofindicators were observedandcompared between thetwogroups.Results：Afterthetreatment，thearousal indexof theobservation group waslowerthanthatofthecontrolgroup，thelowestbloodoxygensaturationatnightwashigherthan thatofthecontrol group，and the apnea index was lower than that of the control group，with statistically significant diferences（ P<0.05） . In terms of polysomnography（PSG）indicators，therespiratory disturbance indexandoxygen desaturationindexof theobservation group waslowerthanthoseofthecontrolgroup，theaverageblodoxygensaturationwashigherthanthatof thecontrolgroupanddifferences between the two groups were statistically significant（ P<0.05 ）. For overall sleep quality，the wakefullness after sleep onset of patientsintheobservationgroupwasbeterthanthatinthecontrolgroup，thelongestsleepdurationwasbeterthanthatinthe control group，and thePSQIscore was lower than that in thecontrol group，with statistically significant differences（ P<0.05） . Afterthe treatment，theincidenceofpoor sleepintheobservatio groupwaslowerthanthatinthecontrolgroup，showingthatthere was a significant difference（ P<0.05） . Conclusion： In the treatment of patients with heart failure combined with pulmonary heart disease andslepapnea，theapplicationof bi-levelnon-invasive ventilationcaneasesymptoms，promoteregularizationof thepatients‘nocturmal breathingrhythm，getback thenormal sleepstages，andsignificantlyimproveslepqualityandcontroladverse sleep conditions such as sleepiness.

KeywordsPulmonary heart disease;Sleepapnea；Chronic heart failure；Bi-level non-invasiveventilator;Sleepquality；Respiratory rhythm；Sleepiness；Oxygen desaturation index

中圖分類號：R541.5;R338.63 文獻標(biāo)識碼：A doi：10.3969/j.issn.2095-7130.2025.04.015

睡眠是一種自然的生理現(xiàn)象，其本質(zhì)是一種脊椎動物自我主動調(diào)節(jié)的過程，目的是維持生命活動而進行的適當(dāng)休息。（剩余5177字）