右美托咪定在老年肺癌圍手術(shù)期應(yīng)用的研究

'rogress in perioperative use of dexmedetomidine in elderly lung cancer patients

Zhang Junhao'，Zhang Dan1，Huo Xingyu2，Zhang Houzhong2 （2號 1 TheSecondNoanBetneHosptalofJilinUniversityChangun3O4;teSecondHspitalofJilinUniversityChangc30041 *Corresponding author： Zhang Houzhong，email： houzhong@ jlu.edu.cn

[Abstract]Elderlypatientsdemonstratediminishedphysiologicalfunctionsandvariouscomorbidities，whichpresentsignificant challenges in the perioperative anesthesia management of lung cancer surgery. Dexmedetomidine， a selective α2 -adrenergic receptoragonist，demonstratesdosdependentfectsincdingsdation，aalgesianxiolysis，ndantisypatheticactivityee detomidinedemostratesteprotectivepotentialacossmultiplergansdurigtheperioperativeeriodoflungancersurgeryintheeld erlyhighlgingitsiiantlicatioalueinalsthsipractie.isticeviteanofo dineanditspotentialfrulti-rganprotetionduringteperioperativeperiodofungcancersugeryinlderlypatints.Ialsodiscus sesrecentadvancesinclinicalanesthesiapractice，imingtoenhancethequalityandsafetyofdexmedetomidie-basedanesthesiamanagement for this demographic.

[Key words] Dexmedetomidine；Elderly；Lung cancer；Anesthesia；Perioperative perio

肺癌是全球最常見的惡性腫瘤，其發(fā)病率（ 12.4% ）和死亡率（ 18.7% ）位居全球惡性腫瘤之首[1]。（剩余13593字）