衰弱在老年2型糖尿病患者社會隔離與認(rèn)知功能間的中介效應(yīng)

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The mediating effect of frailty between social isolation and cognitive function in elderly patients with type 2 diabetes

Wu Nixiao，Dai Xia**，Li Sulan，Xu Zilan，Huang Zheng Department of Nursing，theFirst Afiliated Hospital of Guangxi Medical University，Nanning **Corresponding author：Dai Xia，email： 2655947220@ qq.com

[Abstract]ObjectiveToanalyzethemediatingefectoffrailtybetweensocialisolationandcognitivefunctioninelderlypatientswithtypedabeteselitusMetdsAtotaloflderlypatientswithtype2dabetesmelltusamittedtoteipatie partmentoftheDepartmentofGeriatricEndociologoftheFistAfitedHospitalofGuangxiMedicalUniversityfromOctober2 toFebruary2O24wereselectedbyconveniencesampling.Ageneralinformationquestioaire，theSocialNetworkScaleShortFom， theTilburgFrailtyScale，andtheChineseversionoftheSimpleIntellgentMentalStateExaminationSalewereusedtoinvestigate， andthemediatingefectwereanalyedusingtheProcessplug-ininSPSS26.Osoftware.Results3OOelderlypatientswithtype2diabetes melitus scored 14（9，20）points for social isolation and 103（ 34.33% ）for social isolation；5（3，7）points for frailty and 169 （ 56.33% ）for frailty；25（23，27）points for cognitivefunction and 98（ 32.67% ）for cognitive impairment.The frailty score was negatively correlated with the social isolation score （ r=-0.327 ！ P<0.001 ），the frailty score was negatively correlated with the cognitive function score （ r=-0.394 ， P<0.001 ），and the social isolation was positively correlated with the cognitive function score （ r=0.370 ， （204號 P<0.001 ）.Bootstrap test showed that the indirect effect value was O. 071（95 %CI ： 0. 038-O.116），indicating that the indirect effect was established;the direct effect was 0.148（ ，indicating that weakness played a partial mediating role between social isolation and cognitive function，and theindirect effect（O.O71）accounted for 32.42% of the total effect（O.219）. ConclusionSocialisolation，fraltyndcognitiveimpairmentinelderlypatientswithtype2diabetestypediabetesmelitsareata highlevel，andfrailtyasartaledatigeebetwocialsolationogtiefutioniderlypantsittab tesmelitus，suggestigtatsocialiolationcanotolyirectlyectcoitiefunction，utalsoidiretlectcogiivefuctio through frailty.

V words] Type2diabetesmellitus；Social isolation；Frailty；Cognitivefunction；Mediating effe

我國老年2型糖尿病（Type2diabetesmelli-tus，T2DM）認(rèn)知功能障礙患病率高達(dá) 60%[1] 。（剩余9483字）