T淋巴細胞在慢性阻塞性肺疾病發(fā)生發(fā)展及免疫治療中的作用
關(guān)鍵詞：肺疾病，慢性阻塞性；T淋巴細胞；免疫治療
中圖分類號：R563.9文獻標(biāo)志碼：A文章編號：1001-5779（2025）05-0485-07
DOI：10.3969/j.issn.1001-5779.2025.05.013
Abstract：Tlymphocytes playa keyrole in the occurrence and developmentof chronic obstructive pulmonary disease （COPD）. They are classified into CD 4+ Tlymphocyte subsets and CD8+T lymphocyte subsets according to the expression of clusterofdiferentiation（CD），which mediate inflammatoryresponses and participate in immuneregulation processes in COPDthroughthesecretionofcytokines.WhentheproportionofTcellsubpopulationsisimbalanced，itcanlead to immuneimbalance andaggravate lung tissue damage.Currently，Tlymphocyte-related immunotherapyfor COPD mainly focuseson anti-inflammation and immune regulation，including intervention measuressuch as monoclonal antibodies， vaccines，andchemicalagents.Thisarticlemainlyreviews theroleofTlymphocytes intheoccurrenceanddevelopment of COPD and in immunotherapy，aiming to provide a new theoretical basis for clinical treatment.
Keywords：Pulmonary disease，chronic obstructive；Tlymphocytes；Immunotherapy
慢性阻塞性肺疾?。–hronicobstructivepulmo-narydisease，COPD）是以持續(xù)性氣流受限為主要特征的慢性呼吸道疾病，常表現(xiàn)為持續(xù)性的呼吸道癥狀[]。（剩余18538字）