凌霄痛風(fēng)顆粒提取工藝及質(zhì)量控制研究

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1.貴州中醫(yī)藥大學(xué)藥學(xué)院，貴州貴陽550025；2.貴州中醫(yī)藥大學(xué)第二附屬醫(yī)院藥學(xué)部，貴州貴陽550003

【中圖分類號】R284.2 【文獻(xiàn)標(biāo)志碼】A 【文章編號】1007－8517（2025）09-0059-06

DOI： 10.3969/j .issn.1007-8517.2025.09. zgmzmjyyzz202509014

Research on the Extraction Technology and Quality Control of Lingxiao Tongfeng Granules

ZHANGQiang1 YANG Renhui2YANG Yuanfeng2 LOU Yuling2 ZHOU Xunrong 1，2 W

1.Scholof Pharmacy，Guizhou Universityof Traditional Chinese Medicine，Guiyang 55o025，China；2.Departmentof Pharmacy，theSecondAfiliated Hospital ofGuizhou UniversityofTraditional Chinese Medicine，Guiyang 550o03，China

Abstract：ObjectiveOptimizethe extraction process，and establish thequalitystandardof Lingxiao Tongfeng granules.MethodsWiththecontentofhesperidinandthepasteyieldrateastheevaluationindexes，thebstextractionprocessofLingxiaoTongfeng granules wasselectedbytheorthogonal test method；According totheprovisionsof ChinesePharmacopoeia granules，thecaracter， hesperidincontentandthinlayeridentification（TC）wereestablished.ResultThebestextractionprocessforLingxiaoTongfeng granuleswasadd8timesofwaterfor3Ominuteseachtime；thethinlayeridentificationmethodofCampsisgrandiflora，PlantagodepressaWilldandCitrusreticulataBlancowas established，andthecontentof hesperidininLingxiaoTongfengwasdeterminedConclusionTheextractioprocssestablishdintisstudyisstablendreliable，andthequalitativeandquantitatiemethodetablishdis convenient and reliable，which can be used as the quality control method of Lingxiao Tongfeng granules.

KeyWords：Lingxiao Tongfeng Particles；Orthogonal Test；Quality Control；TLC；Hesperidin

凌霄痛風(fēng)顆粒原方是貴州中醫(yī)藥大學(xué)第二附屬醫(yī)院風(fēng)濕免疫科治療痛風(fēng)的臨床驗方。（剩余7615字）