一種創(chuàng)新的輸尿管回腸吻合方法

——基于兔模型的磁吻合

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ABSTRACT：ObjectiveTo investigate the feasibility of magnetic anastomosis for uretero-ileal anastomosis using experimental rabbit models.MethodsSix experimental rabbits were used as the models.The lower part of the left ureter was cut with scissors，the daughter magnet （DM） was placed in the middle of the ureter，and the distal end of the ureter was ligated.After that，the ileum wall was opened，the parent magnet （PM） was inserted through it，the positions of the PM and DM were adjusted so that their ends were attracted to each other，and then ileum wall incision was sutured.The operation time，intraoperative blood loss，postoperative complications and magnet discharge time were recorded.Two weeks after operation，left ureterography was performed to obtain the specimens of the uretero-ileal anastomosis，and to observe the patency of the anastomosis.The formation of the anastomosis was observed with naked eyes and light microscope.ResultsUretero-ileal magnetic anastomosis was performed successfully in 6 experimental rabbits.The operation time was 2839（32.50±3.94） min，and the intraoperative blood loss was less than 5 mL.The rabbits recovered well after operation，and no complications were observed.All animals survived to the end point of observation.The disconnection time of magnet after operation was 913（10.83±1.72） days.The gross specimen showed that the anastomosis was patent.The histological observation showed that the mucosa of the anastomosis was continuous and smooth，and the anastomosis was well formed.ConclusionMagnetic anastomosis is feasible for uretero-ileal anastomosis with simple operation and good anastomosis formation.After further experimental verification，this technique is expected to be used in clinical practice.

摘要：目的使用實(shí)驗(yàn)兔動(dòng)物模型，探討磁吻合技術(shù)用于輸尿管回腸吻合的可行性。（剩余6489字）