一體位機(jī)器人輔助腹腔鏡與后腹腔鏡腎輸尿管切除術(shù)治療上尿路尿路上皮癌的療效比較

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ABSTRACT：ObjectiveTo explore the clinical safety and efficacy of a single-position robot-assisted radical nephroureterectomy （RRUN） in the treatment of upper tract urothelial carcinoma （UTUC）.MethodsA retrospective study was conducted on 136 UTUC patients who underwent RRUN （n=35） and  laparoscopic radical nephroureterectomy （LRUN，n=101） in our hospital during Dec.2020 and Aug.2023.The perioperative and safety indicators of the two groups were compared.The intravesical recurrence-free survival （IVRFS），recurrence-free survival （RFS），and overall survival （OS） of the two groups were compared using Kaplan-Meier method.ResultsThere were no significant differences in the baseline data between the two groups （P>0.05）.All surgeries were successfully completed without conversion to open surgery.RRUN demonstrated superior perioperative outcomes compared to LRUN in overall postoperative complication rate [37.1%（13/35） vs. 56.4%（57/101）]，postoperative hospital stay [6（5，7） days vs. 7（6，8） days]，and catheter indwelling time [3（2，4）  days vs. 4（3，5）days]，with statistically significant differences （P<0.05）.Safety indicators of both surgical approaches were similar （P>0.05）.Survival analysisshowed no significant difference in oncological outcomes between the two groups [IVRFS （1 year：92.1%，2 years：85.2%），RFS （1 year：82.4%，2 years：74.9%），OS （1 year：90.6%，2 years：84.2%）] （P>0.05）.Conclusion Compared with retroperitoneal LRUN，single-position RRUN for UTUC demonstrates comparable safety and oncological efficacy，while offeringsignificant advantages in perioperative outcomes such as reducing postoperative complication rate and shortening hospitalstay.

摘要：目的探討一體位機(jī)器人輔助腹腔鏡腎輸尿管切除術(shù)治療上尿路尿路上皮癌（UTUC）的臨床安全性和療效。（剩余10329字）