人口和臨床特征對精神分裂癥患者生活質(zhì)量的影響

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DOI：10.16424/j.cnki.cn32-1807/r.2025.04.016

引文格式：張沛云，等.人口和臨床特征對精神分裂癥患者生活質(zhì)量的影響[J].南通大學(xué)學(xué)報（醫(yī)學(xué)版），2025，45（4）：389-392.

[關(guān)鍵詞]精神分裂癥；生活質(zhì)量;陰性癥狀；認(rèn)知功能；社會支持[中圖分類號]R749.3 [文獻(xiàn)標(biāo)志碼]A [文章編號] 1674-7887（2025）04-0389-04

Theimpactofdemographicandclinicalcharacteristicson thequalityoflifeofpatientswithschizophrenia*

ZHANGPeiyun*，LIU Chao，YAN Qi， ZHOU Chunying，BAO Juan，QIN Qianqian，TANG Kaihong** （Department of Psychiatry，NantongFourthPeople'sHospital，Jiangsu226005）

[Abstract]Objectie：Toinvestigatethedemographicandclinicalcharacteristicsofschizophreniapatientsandexplorethe factorsnfluencingtheirqualityoflife.Methods：Atotalof82malepatientswithschizophreniawhometthediagnosticcriteria forschizophreniaaccordingtoICD-1Oandtheinclusioncriteriawereselectedastheresearch subjects.Theywereassesed usingthegeneral informationquestionnaire，thepositiveandnegativesyndromescale（PANSS），therepeatablebatteryforthe assessmentofneuropsychologicalstatusRBANS），thesocialsupportratingscale（SSRS），andtheshizophreniaqualityofiescale （SQLS）.Results：Durationofilless，occupation，andBMcharacteristicsafectthequalityoflifeofshizophreniapatints. The totalscoreofRBANSanditssubscalescoresforimmediatememoryverbalfunction，atention function，anddelayed memory were negatively correlated with the total score of SQLS（ P <0.05）. The positive symptoms， negative symptoms，and general symptoms of patients were positively correlated with the total score of SQLS（ Pe <0.05）.The utilization of social support as measured bythe SSRS was negatively correlated with the total score of SQLS（ P <0.01）.Conclusion：Duration of illness，BMI， negativesymptoms，atentionfunction，andtheutilizationofsocial supportarefactorsthatinfluencethequalityoflifeof schizophrenia patients.

[Key Words]schizophrenia; quality of life; negative symptoms; cognitive function; social support

精神分裂癥是一種嚴(yán)重精神障礙，病情反復(fù)遷延，往往需要長期抗精神病藥物治療，患者軀體與心理承受著雙重痛苦，引起主觀幸福感和生活能力下降，嚴(yán)重者可造成不同程度的精神殘疾。（剩余6267字）