氨茶堿與甲潑尼龍琥珀酸鈉聯(lián)合治療慢性阻塞性肺病急性 加重期的臨床效果及對(duì)血清CRP水平、 PaO2 的影響
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關(guān)鍵詞：氨茶堿；甲潑尼龍琥珀酸鈉;慢性阻塞性肺病急性加重期；CRP; PaO2 中圖分類號(hào)：R563 文獻(xiàn)標(biāo)識(shí)碼：A
DOI：10.3969/j.issn.1006-1959.2025.13.030 文章編號(hào)：1006-1959（2025）13-0150-04
Abstract：OectieTexplotlcalofmioyineobdielpredsoloesodmsucateintreafte exacerbation of chronic obstructive pulmonary disease and its effect on serum CRP level and PaO2. Methods A total of 6O patients with acute exacerbationofronctructiepulmoardseaseadmitedtoYushanCountyHuanisiHospitalfroMa1toMa24weeeletd theresearcectscodingtoeadomumberablemetod，teyeredvidedintocontrolgounddyoup，ith3Opatitsc group.Thecotroloupastreaedwitnohlnendtesdopsreadwitethlpredsoloeucateoef thecontrolgoiddiaiti capacityinthefirstsecondtoforcedvitalcapacity（FEV/FCV），seruminflammatoryfactorlevels[tumornecrosisfactor ??α∝ （TNF-α），interleukin-8 （IL-8），procalcitonin （PCT），C-reactive protein （CRP）]， blood gas index levels ?pH ，arterial partial pressure of carbon dioxide （PaCO2），arterial partial pressure of oxygen （Pa02）- werecomparedbetweenthetwogroups.ResultsThetotalefectiverateof treatmentinthestudygroupwashigherthan that in the control group（ P<0.05） .Thelung function indexes of the study group were better than those of the control group（ P<0.05） .Thelevelsof serum inflammatory factors in the study group were lower than those inthe control group（ P<0.05） .The level of PaCO2 in the study group was lower than that in the control group，while the level of PaO2 was higher than that in the control group （P<0.05） .Conclusion The combination of aminophyllneandethlpredisolosoduciateasadefinitecliicalectitetrmentofpatintsitacueeacbationf chronicobstructivepulmonarydiseasehichcanimprovetheungfuctionofpatients，educetheilammatoryesponseofpatientspoe the clinical effectand bloodgasindexlevel，andisworthyof clinical application.
Keywords：Aminophyline;Methylprednsolonesodiumsuinate;Acuteexacerbationofchronicobstructivepulmonarydisease;CRP; PaO2
慢阻肺（chronic obstructive pulmonary disease，COPD）在臨床中極為常見(jiàn)。（剩余5654字）