不同劑量布地奈德霧化吸入對老年慢性阻塞性肺病急性加重期患者的治療效果觀察

打開文本圖片集

中圖分類號：R563 文獻(xiàn)標(biāo)識碼：A

DOI：10.3969/j.issn.1006-1959.2025.13.018 文章編號：1006-1959（2025）13-0098-05

Abstract：ObjectieTvestigatetetrapeuticetofdieretossofudesodeforoslilaoolderlypatintswihute exacerbationofonicstructiveumoarydiseaseMetodsUsingteadommbertablemetodotalyOderlyatientsithcute exacerbationofhocbstructiepulmoarydiseasedmitedtouichangCountyeoplesHospitalduringtheperiodfroJanuarytJay 2024wereandlylaedtoooodnsdoachsisgofatintseodoreatioal dose（mg/ti）fdesodespsioforalatiodtdoastreatediose（tsofdesodespr inhalationecalacngcodeatoeined（FEV）dialapacit expiratory flow （PEF）]，inflammatory factors [interleukin- ?8 （IL-8），tumor necrosis factor -a （TNF-a），procalcitonin （PCT）]，immune function （CD3 + ， CD4CD8s ResultsCompdioptdodigealsoseatesellsvelsfVVCEVVd after treatment （P<0.05）.The levels of IL-8，TNF- α ，and PCT were lower in the study group than those in the control group P<0.05） .Additionally， the study group showed significantly higher CD 3+ ，CD 4+ ，andCD4+/CD8 ζ+ levels，and lower CD8 + levels than those in the control group （P<0.05）. No statistically significant diference was observed in adverse reaction rates between the groups（ P >0.05）.Conclusion High-dose（2 mg/times） budesonideforoslialatioisetiveintraetofdelatitsituteecebatioofocructieulmoasese whichcapengidoftsetosefdceio It is worthy of clinical application.

KeyWords：Diferentdose;Budesonide;Aerosolihalation;Elderly;Acuteexacerbationofchronicbstructivepulmonarydiseae

慢性阻塞性肺病急性加重期的病情發(fā)展速度較快，而且容易反復(fù)發(fā)作，對患者的生命安全造成了嚴(yán)重的威脅，且該病具有較高的致殘率和致死率，對患者和家屬都是一種沉重的負(fù)擔(dān)。（剩余5740字）