不同劑量利伐沙班治療老年心力衰竭合并房顫患者的臨床效果及安全性對(duì)比
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中圖分類(lèi)號(hào)：R541.6；R541.7+5 文獻(xiàn)標(biāo)識(shí)碼：A
DOI：10.3969/j.issn.1006-1959.2025.13.028 文章編號(hào)：1006-1959（2025）13-0142-04
Abstract：OjectieTsudtelicalfndsfetyofdifeentdosofaroabainetreamentoflderlypatientswihartfalure andatrialiliesol2trlirtflcdralr hospitalweredividedintoacontrolgoupandanobservationgroup（29casespergoup）usingaandomumbertablemethod.Thecontrolgroup received rivaroxaban with a dose of 20mg/d ，while the observation group received rivaroxaban with a dose of 10mg/d .Theclinical efficacy，cardiac functionineatdeeofdactddefdosdebovstsd betweenhetgouResultshrsatisallysiiiantdieineotaletivatefrmntetwtoos（ P> （20 0.05）.TheefttruarjetiofrctonLVEFoftetogousasertantatforetreamntndedstoliceftriclar posterior wallthickness（LVPWD） was lower than that before treatment（ PΦ <0.05），but there wasno statistically significant difference inLVEFand LVPWD between the two groups after treatment（ P>0 0.05）.The D-dimer（D-D）of the two groups was lower than that before treatment，and the prothrombitsoert）utsatistllteid two groups after treatment（ P>0.05 ）.Theincidences of adversereactionsand cardiovascularandcerebrovascular events intheobservationgroup were bothlowerthantoseinthotrolgoupPO5）.Cocusioneliicaletsoffretdossofivaroabanintetreamntfelderly patientswitartedloallpeduodedlatioo However， 10mg/d rivaroxabanhasfeweradversereactionsandlowerincidenceofcardiovascularandcerebrovascularevents，ndhasrelativelybetter treatment safety.
KeyWords：Differentdoses;Rivaroxaban;Elderly;Heartfailure;Atrial fibrillation;Safety
心力衰竭（heartfailure）是臨床常見(jiàn)的疾病，其發(fā)生與多種因素相關(guān)[]，而房顫（atrialfibrillation）是心力衰竭常見(jiàn)的并發(fā)癥之一，會(huì)加重病情，增加心腦血管不良事件發(fā)生率，嚴(yán)重威脅患者生命安全。（剩余5054字）