降調(diào)節(jié)誘導(dǎo)排卵方案聯(lián)合當(dāng)歸地黃飲 對凍融胚胎移植子宮內(nèi)膜容受性及妊娠結(jié)局的影響
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The Effect of the Combination of Down-regulation Ovulation Induction Protocol with Danggui Dihuang Decoction on Endometrial Receptivity and Pregnancy Outcomes in Frozen Thawed Embryo Transfer/YE Xiuxian，CHENWeiwei，CHAOShibin.//Medical InnovationofChina，2025，22（18）：143-148
[Abstract] Objective：To investigate the efects of down-regulation ovulation induction protocol with Danggui Dihuang Decoction on endometrial receptivity and pregnancy outcomes in frozen thawed embryo transfer. Method： A retrospective analysis was conducted on the clinical data of 12O patients who underwent frozen thawed embryo transferinthe Afliated HospitalofFuzhou Medical Colege，Nanchang Universityfrom January 2023 to March 2024.According to the treatment method，they were divided into a study group （6O cases of down-regulation ovulation induction protocoland Danggui Dihuang Decoction）and a control group（6O cases of down-regulation ovulationinductionprotocol）.Theuterinearterybloodflowparameters，endometrialreceptivity，hormone levels，and pregnancy outcomes were observed and compared between the two groups.Result： Before treatment， there were no significant diferences intheuterinearterypulsatilityindex （PI），resistance index （RI），systolic/diastolic blood flow （S/D），follicle-stimulating hormone （FSH）， luteinizing hormone （LH），estradiol （E2） ， serum progesterone （P） levels between the two groups （ P> 0.05）.After treatment，the levels of RI，PI， S/D，LH，biochemical pregnancy rate， spontaneous abortion rate，and ectopic pregnancy rate were lower in the study group，while the endometrial receptivity rate，F(xiàn)SH， E2 ，Plevels，and clinical pregnancy rate were higher，with significant differences（ P <0.05）. Conclusion： The useof down-regulation ovulation induction protocoland Danggui Dihuang Decoction in the treatment offrozen thawed embryotransfer patients can effectively enhance blood flow perfusionunderthe endometrium，improve endometrial morphology，regulate relevant hormone levels，and has a positive effect on pregnancy outcomes.
[Key words] Danggui Dihuang Decoction Freeze thawed embryo transferEndometrial receptivity Pregnancy outcome
First-author'saddress：FuzhouMedicalCollege，Nanchang University，F(xiàn)uzhou3441oo，China doi：10.3969/j.issn.1674-4985.2025.18.033
隨著輔助生殖技術(shù)的不斷發(fā)展，凍融胚胎移植已成為解決眾多不孕不育問題的重要手段之一凍融胚胎移植旨在解決多種復(fù)雜情況下的生育需求，例如新鮮取卵周期中出現(xiàn)卵巢過度刺激綜合征風(fēng)險、子宮內(nèi)膜發(fā)育與胚胎發(fā)育不同步、患者身體狀況不適宜立即進(jìn)行胚胎移植等問題，通過將胚胎冷凍保存，待合適的時機(jī)進(jìn)行移植，為患者提供了更多的生育機(jī)會[2]。（剩余7708字）