觀察參附注射液對急性心力衰竭患者 睡眠質(zhì)量的療效

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關鍵詞急性心力衰竭;參附注射液;中西醫(yī)結合;療效;炎癥介質(zhì);生命質(zhì)量;睡眠質(zhì)量;心血管疾病

Observation of the Therapeutic Effects of Shenfu Injection on Sleep Quality in Patients with Acute H

DINGHaiba

（Nanjing Hospital of Traditional Chinese Medicine，Nanjing 21oo22，China）

AbstractObjective：ToexploretheefectsofcombinedtreatmentofShenfu injectionand westernmedicineonpatients withacuteheartfailure，andtoobserve itsefectsonpatients’slepquality.Methods：Atotalof2OOpatientswithacuteheartflureadmitedto theEmergencyDepartmentofNanjing HospitalofTraditional Chinese Medicinefrom January219 toJanuary2024 were selected asthe studysubjects.They wererandomlydividedintoacontrol groupandanobservationgroupusingarandom number table metod，with10Opatientsineachgroup.Thecontrolgroupreceivedbasictreatment intervention；Theoservationgroupreceived Shenfu injectiononthebasis ofthecontrol group.The Pitsburgh SleepQuality Index（PSQI）wasused tocompare the changes in sleepqualitybetween two groups beforeandafterintervention.The Minnesota HeartFailure QualityofLife Scale（MLHFQ）wasusedtoevaluate thelifequalityof thetwo groups beforeandafterintervention.The myocardial injurymarkers（ncluding N-terminal probrainnatriureticpeptide levels，creatinekinase，creatine kinaseisoenzmelevels）and inflammatoryfactors （including high-sensitivityC-reactiveproteinandtumornecrosisfactoralpha）ofthetwogroupswereobserved.ResultsAfter treatment，the MLHFQscoresoftheobservationgroupweresignificantlylowerthanthoseof hecontrolgroup，andthePSQIscores of theobservationgroupweresignificantlylowerthanthoseofthecontrolgroup.Aftertreatment，thelevelsofN-terminalprobrain natriuretic peptide，creatine kinase，creatine kinase isoenzyme，high-sensitivity C-reactive protein，andtumor necrosis factor α in bothgroups decreased，andtheobservationgroupwassignificantlylowerthanthecontrol group.Thediferencesbetweehetwo groups were statistically significant（ P<0.05 ）. Conclusion：The combination of Shenfu injection and western medicine treatment caneffectivelyreducethelevelsofcardiacfunctionrelatedindicatorsand inflammatoryfactors inpatientswithacutehartfailure. It can also improve the daily life quality and sleep status of patients.

KeywordsAcute heartfailure;Shenfu injection；Combinationof traditional Chinesemedicineand western medicine；Therapeutic effect；Inflammatory factors；Life quality； Sleep quality；Cardiovascular disease

中圖分類號： R541.6+1 ;R338. 63 文獻標識碼：A doi：10.3969/j. issn.2095 -7130.2025.02.004

心力衰竭是一種嚴重的心血管疾病，其表現(xiàn)為不同程度的呼吸困難、肢體水腫、全身乏力以及日?；顒幽芰κ芟?。（剩余5341字）