二甲雙胍聯(lián)合優(yōu)思悅治療肥胖型多囊卵巢綜合征的臨床效果分析

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【摘要】目的：分析在優(yōu)思悅基礎(chǔ)上服用二甲雙胍對(duì)肥胖型多囊卵巢綜合征患者性激素、胰島素抵抗的改善作用。方法：選取100例肥胖型多囊卵巢綜合征患者作為研究對(duì)象，并劃分至兩個(gè)小組內(nèi)，分別給予單一優(yōu)思悅治療（對(duì)照組）和優(yōu)思悅聯(lián)合二甲雙胍治療（觀察組），連續(xù)治療3個(gè)療程，并觀察兩組患者的療效。結(jié)果：治療后，相較于對(duì)照組，觀察組總有效率、排卵率、妊娠率及雌二醇均更高，BMI、IRI、促卵泡生成素、促黃體生成素以及睪酮均更低，各項(xiàng)數(shù)據(jù)均存在差異性，P

【關(guān)鍵詞】二甲雙胍；優(yōu)思悅；肥胖型多囊卵巢綜合征；性激素水平

基金項(xiàng)目：2023年度廣西壯族自治區(qū)衛(wèi)健委西醫(yī)類別自籌經(jīng)費(fèi)科研課題《體重管理聯(lián)合二甲雙胍在肥胖型多囊卵巢綜合癥合并不孕患者中的臨床應(yīng)用》（Z-A20230309）

Clinical efficacy analysis of metformin combined with Yousiyue in the treatment of obese polycystic ovary syndrome

WEI Fangxiu， CHEN Mei， MO Meichun， MO Linling， LI Cuiming

Guangxi Zhuang Autonomous Region Maternal and Child Health Hospital， Nanning， Guangxi 530000， China

【Abstract】Objective：To analyze the improvement effect of taking metformin based on Yousiyue on sex hormones and insulin resistance in patients with obese polycystic ovary syndrome.Methods：100 patients with obese polycystic ovary syndrome were selected as the research subjects，and they were divided into two groups.They were treated with single Yousiyue （the control group） and Yousiyue combined with metformin （the observation group） for three consecutive courses of treatment，and the therapeutic effects of the two groups of patients were observed.Results：After treatment，compared to the control group，the total effective rate，ovulation rate，pregnancy rate and estradiol of the observation group were higher，the BMI，IRI，follicle stimulating hormone，luteinizing hormone and testosterone were lower，and there were differences in all data，P

【Key Words】Metformin； Yousiyue； Obese polycystic ovary syndrome； Sex hormone levels

多囊卵巢綜合征是一種女性常見的內(nèi)分泌代謝異常病癥，一般高發(fā)于育齡期，近年來在青春期中的發(fā)病率也較高[1]。（剩余4202字）