達(dá)格列凈聯(lián)合二甲雙胍治療T2DM患者的臨床療效研究

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【摘要】目的：分析達(dá)格列凈聯(lián)合二甲雙胍治療T2DM患者的臨床療效。方法：將2023年12月—2024年6月期間我科收治的96例T2DM患者納入實驗，利用隨機(jī)數(shù)字表法生成A、B兩個實驗組，將A組定義為二甲雙胍單藥治療組，將B組定義為達(dá)格列凈聯(lián)合二甲雙胍治療組，對比兩組的治療效果。結(jié)果：B組治療總有效率高于A組（P0.05）；口服無水葡萄糖后0.5、1、1.5及2h，B組的血糖水平均低于A組（P0.05）；治療后，B組患者的各項DSQL得分均高于A組（P

【關(guān)鍵詞】達(dá)格列凈；二甲雙胍；T2DM

Clinical efficacy of dapagliflozin combined with metformin in the treatment of T2DM patients

JIA Mangmang

Suzhou Ninth People’s Hospital， Suzhou， Jiangsu 215200， China

【Abstract】Objective：To analyze the clinical efficacy of dapagliflozin combined with metformin in the treatment of T2DM patients. Methods：96 T2DM patients admitted to our department from December 2023 to June 2024 were included in the experiment，and two experimental groups A and B were generated by the random number table method.Group A was defined as the metformin monotherapy group，and group B was defined as the dapagliflozin combined with metformin treatment group.The therapeutic effects of the two groups were compared.Results：The total effective rate of treatment in group B was higher than that in group A （P0.05）；The blood glucose levels in group B were lower than those in group A at 0.5h， 1h， 1.5h and 2h after oral anhydrous glucose （P0.05）；After treatment，the scores of DSQL in group B were higher than those in group A （P

【Key Words】Dapagliflozin； Metformin； T2DM

T2DM即二型糖尿病，是一種非胰島素依賴型糖尿病，在糖尿病患者中最為常見，以中老年患者居多，胰島素相對不足是其最典型的臨床特點，患者可因胰島素抵抗、胰島素分泌不足等因素導(dǎo)致血糖異常升高[1]。（剩余4501字）