在肺結(jié)核細(xì)菌檢測中運(yùn)用熒光定量PCR檢測法的臨床價(jià)值

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【摘要】目的：分析在肺結(jié)核細(xì)菌檢測中運(yùn)用熒光定量PCR檢測法的臨床價(jià)值。方法：本文總共納入88例觀察對(duì)象，均是我院2016年5月—2021年5月收治的疑似塵肺合并肺結(jié)核患者，對(duì)88例患者開展熒光定量PCR與痰涂片抗酸染色檢測。將臨床診斷作為參照依據(jù)，比較兩種方法的檢測結(jié)果。結(jié)果：在檢出率、敏感度、特異度、陽性預(yù)測值以及陰性預(yù)測值上，熒光定量PCR明顯高于痰涂片抗酸染色檢測（P

【關(guān)鍵詞】肺結(jié)核；細(xì)菌檢測；熒光定量PCR檢測法；臨床價(jià)值

Clinical value of fluorescence quantitative PCR detection method in the detection of pulmonary tuberculosis bacteria

WEN Xiaoping

Department of Laboratory， Huizhou Occupational Disease Prevention and Control Hospital， Huizhou， Guangdong 516001， China

【Abstract】Objective： To analyze the clinical value of fluorescent quantitative PCR detection method in the detection of pulmonary tuberculosis bacteria. Methods： A total of 88 observation objects were included in this study， all of whom were patients with suspected pneumoconiosis complicated with pulmonary tuberculosis admitted to our hospital from May 2016 to May 2021. Fluorescence quantitative PCR and sputum smear acid-fast staining were performed on 88 patients. The clinical diagnosis was used as a reference to compare the test results of the two methods. Results： The detection rate， sensitivity， specificity， positive predictive value and negative predictive value of fluorescence quantitative PCR were significantly higher than those of sputum smear acid-fast staining（P

【Key？Words】Pulmonary tuberculosis； Bacterial detection； Fluorescence quantitative PCR detection method； Clinical value

肺結(jié)核在臨床上比較常見，是一種慢性的傳染病，患者在感染結(jié)核桿菌后不一定及時(shí)出現(xiàn)癥狀，當(dāng)患者的抵抗力降低情況下才會(huì)引起疾病[1]。（剩余4278字）