腹腔鏡膀胱癌根治術(shù)中采用吲哚菁綠熒光顯像與標(biāo)準(zhǔn)淋巴結(jié)清掃臨床療效的隨機(jī)對(duì)比研究

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ABSTRACT：ObjectiveTo investigate the efficacy，safety and feasibility of regional lymph node dissection in laparoscopic radical surgery for bladder cancer under the guidance of indocyanine green fluorescence imaging.MethodsA total of 30 patients with muscle invasive bladder cancer （T2/T3NxM0） who volunteered to enter the clinical trial were randomly divided into the indocyanine green imaging guided laparoscopic regional lymph node dissection group （n=15） and the standard pelvic lymph node dissection group （n=15）.The number of positive lymph nodes，operation time，intraoperative bleeding volume，incidence of lymph leakage，and tumor recurrence and metastasis rate 2-year after surgery were collected.ResultsThe number of positive lymph nodes was （4.20±1.66） and （4.60±1.72） respectively in the indocyanine green and standard groups，with no statistically significant difference （P>0.05）.There were no statistically significant difference in the tumor recurrence and metastasis rates 2-year after surgerybetween the two groups （P>0.05）.However，the indocyanine green group had shorter operation time，less intraoperative bleeding volume，and lower incidence of lymphatic leakage than the standard group （P<0.05）.ConclusionIndocyanine green fluorescence imaging guided laparoscopic lymph node dissection has comparable clinical efficacy to standard lymph node dissection，but with fewer complications.

摘要：目的探討吲哚菁綠熒光顯像引導(dǎo)下腹腔鏡膀胱癌根治術(shù)中區(qū)域淋巴結(jié)清掃的有效性、安全性及可行性。（剩余6061字）