運(yùn)動(dòng)發(fā)揮抗炎作用改善神經(jīng)炎癥相關(guān)抑郁癥的研究進(jìn)展
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關(guān)鍵詞：運(yùn)動(dòng)；抑郁癥；神經(jīng)炎癥；抗炎；運(yùn)動(dòng)處方
中圖分類號：R749.4；G807.4文獻(xiàn)標(biāo)識碼：A 文章編號：1000-503X（2025）02-0191-07
DOI：10.3881/j. issn.1000-503X.15991
Research Progress in the Anti-Inflammatory Effect of Exercise in Ameliorating Neuroinflammation- Related Depression
ZHANG Zhixin1，2，GUO Qi1，CHEN Xiaoyu Colegeof Rehebilitation Sciences，Shanghai Universityof Medicineand Health Sciences，Shanghai 2O1318，China Tianjin Key Laboratoryof Exercise Physiologyand Sports Medicine，Institute of Sport，Exercise and Health， TianjinUniversityofSport，Tianjin，China
Corresponding author：CHEN Xiaoyu Tel：18822202275，E-mail：1334427886@qq.com
ABSTRACT：Depression is an affective disorder caused by multiple factors，and its pathogenesis is stil unclear.However，in recent years， studies have found an association between neuroinflammation and depression， which is mainlyreflected inthe interaction of their pathogeneses，such as abnormalitiesof monoamine neurotransmiters inthe brain，dysregulation of thehypothalamic-pituitary-adrenal axis，anddysfunction of neurogenesis. Currently，exerciseas a therapy for depression has attracted widespread attntion. By reviewing relevant research reports，this article summarizes that exercise allviates neuroinflammation by playing an anti-inflammatory role， thus improving the mood-related pathway to treat depresion.Furthermore，thisarticle explores theefects of different exercise prescriptions on the anti-inflammatory role of exercise，aiming to provide new scientific ideas for the treatment of depression associated with neuroinflammation.
Key words：exercise；depression；neuroinflammation；anti-inflammatory；exercise prescription
ActaAcadMedSin，2025，47（2）：191-197
抑郁癥是一種最常見的精神疾病，以情緒低落、快感缺失和社交障礙等表現(xiàn)為主。（剩余19111字）