下肢動脈硬化閉塞癥置管溶栓聯(lián)合腔內(nèi)治療的應(yīng)用研究

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[摘要] 目的 對比置管溶栓結(jié)合腔內(nèi)介入治療下肢動脈硬化閉塞癥（ASO）的臨床價值。方法 納入2015年9月至2020年9月山東省濰坊市益都中心醫(yī)院收治的ASO患者90例，隨機分為干預(yù)組、參照組，各組均45例，前者提供置管溶栓+腔內(nèi)介入治療，后者僅行腔內(nèi)介入治療，對比兩組療效及臨床指標(biāo)。結(jié)果 干預(yù)組血管開通及截肢率均優(yōu)于參照組，差異有統(tǒng)計學(xué)意義（P

[關(guān)鍵詞] 介入治療;下肢動脈硬化閉塞癥;置管溶栓;臨床療效

[中圖分類號] R543.5         [文獻標(biāo)識碼] B         [文章編號] 1673-9701（2022）10-0107-04

[Abstract] Objective To investigate the clinical value of catheter-directed thrombolysis combined with endovascular intervention for lower extremity arteriosclerosis obliterans （ASO）. Methods A total of 90 patients with ASO admitted to Weifang Yidu Central Hospital of Shandong Province from September 2015 to September 2020 were included in this study. They were divided into the intervention group and the control group according to the randomized grouping principle， with 45 patients in each group. The intervention group was treated with catheter-directed thrombolysis + endovascular intervention， while the control group was treated with endovascular intervention. The efficacy and clinical indexes were compared between the two groups. Results The vascular patency rate was higher and the amputation rate was lower in the intervention group than those in the control group， with statistically significant differences （P

[Key words] Intervention; Lower extremity atherosclerosis obliterans; Catheter-directed thrombolysis; Clinical efficacy

下肢動脈硬化閉塞癥（lower extremity atherosclerosis obliterans，ASO）主要是指動脈粥樣硬化造成動脈閉塞或狹窄誘發(fā)的下肢缺血疾病，患者主要表現(xiàn)為下肢缺血性疼痛[1]、肢體壞疽與間跛等，常合并全身多處動脈硬化病變，影響病人的身體健康及壽命。（剩余7702字）