新四聯(lián)治療心衰伴心臟擴(kuò)大患者的臨床效果及安全性分析

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中圖分類號(hào)：R541.6 文獻(xiàn)標(biāo)識(shí)碼：A文章編號(hào)：1006-1959（2025）12-0091-04

DOI：10.3969/j.issn.1006-1959.2025.12.018

Clinical Effectand SafetyAnalysisof NewQuadruple TherapyinPatientswith Heart Failureand Cardiac Enlargement

LIU Hongyue，YANG Peiliang

（DepartmentofCardiology，HuazhouDistrictPeople'sHospitalofWeinanCityWeinan714199，Shaani，hina）

Abstract：ObjectiveToobserethecliicaleetandafetyofnwuadruplethrapyinpatientswitheartfailureandcardacelargeen Methodstotalof8patietsiteartflurendcadclargeenttreatedatorospitalfropriltoApril23relldnd randomlydividedintoacontrolgroupndanobservationgroup（39paientspergroup）usingaandomnumbertable.Thecontrolgoupreceived conventioalaileosadiduplaalcctaee indices，cideedcdtsddeacseadeoosulsetiod the total effective rate （94.87 % ） than that in the control group （82.05 % ）（P<0.05）.While，both groups had higher the left ventricular ejection fraction （LVEF）andlowertetticuladssolicaeterVEDndfttriculadstolicaeerVED）tanatotrat meanwhilecompared with control group，the observation group had higher LVEFand lower theLVESDand LVEDD （ P< <0.05）.Both groups had higher thesystolicakoitdstcaloiDffedcooea with control group，the observation group had higher SPV and DPV（ P< 0.05）.The observation group had lower the incidence of adverse cardiac events （5.13 % ） than that in the control group （15.38 % 0 P<0.05 ）.The observation group had lower the incidence of adverse reactions （7.69 % ） than that in the control group （17.95 % ）（P

Keywords：eupleayHatfueicagt;gotesitoeprlinolucooe 2; β -blockers;Aldosteronereceptor antagonists

心衰（heartfailure）是臨床常見的疾病，具有病情嚴(yán)重、病死率高、病程長、易反復(fù)的特點(diǎn)，嚴(yán)重威脅患者的生命健康。（剩余5145字）