國(guó)內(nèi)獻(xiàn)血者歸隊(duì)的現(xiàn)狀與思考

［摘要］ 受試驗(yàn)方法學(xué)、試劑、標(biāo)本狀態(tài)和獻(xiàn)血者個(gè)體因素等影響，部分獻(xiàn)血者因血液篩查單試劑反應(yīng)性被永久屏蔽，因未做進(jìn)一步的確證試驗(yàn)可能為假反應(yīng)性，對(duì)此國(guó)內(nèi)很多采供血機(jī)構(gòu)在進(jìn)行獻(xiàn)血者的歸隊(duì)工作。本文就獻(xiàn)血者歸隊(duì)的定義、歸隊(duì)指南的版本更新、國(guó)內(nèi)采供血機(jī)構(gòu)進(jìn)行歸隊(duì)工作情況作一綜述。

［關(guān)鍵詞］ 無(wú)償獻(xiàn)血；假反應(yīng)性；獻(xiàn)血者歸隊(duì)

［中圖分類號(hào)］ R457

［文獻(xiàn)標(biāo)志碼］ A

［文章編號(hào)］ 2096-5532（2024）04-0630-03doi：10.11712/jms.2096-5532.2024.60.126

［開(kāi)放科學(xué)（資源服務(wù)）標(biāo)識(shí)碼（OSID）］

［網(wǎng)絡(luò)出版］ https：//link.cnki.net/urlid/37.1517.R.20240919.1020.004;2024-09-20 08：23：39

Current status and reflection of the reentry of blood donors in China

FENG Qiuxia， HOU Yun， PAN Haiping， YANG Zhongsi（Qingdao Blood Center， Qingdao 266071， China）; ［Abstract］Due to the influence of test methodology， reagents， specimen status， and individual factors of blood donors， some blood donors have been permanently shielded due to single-reagent reactivity in blood screening， which might be false reactivity due to the lack of further confirmatory tests， and in this regard， blood collection and supply institutions in China are carrying out the reentry of blood donors. This article reviews the definition of blood donor reentry， version updates of reentry guidelines， and the reentry work of blood collection and supply institutions in China.

［Key words］voluntary blood donation; false reactive; blood donor reentry

隨著酶聯(lián)免疫吸附試驗(yàn)（ELISA）方法和核酸檢測(cè)技術(shù)（NAT）的發(fā)展，試劑靈敏度不斷提高，在降低血液輸血風(fēng)險(xiǎn)的同時(shí)不可避免導(dǎo)致檢測(cè)結(jié)果假反應(yīng)性增多[1-6]，如梅毒螺旋體（TP）篩查反應(yīng)性標(biāo)本經(jīng)確證后，陽(yáng)性率僅約0. 28%[7]。（剩余7738字）