用于即時(shí)檢驗(yàn)的微流控紙基分析設(shè)備的研究進(jìn)展

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Abstract： Point-of-care testing （POCT） refers to a category of diagnostic tests that are performed at or near to the site of the patients （also called bedside testing） and is capable of obtaining accurate results in a short time by using portable diagnostic devices， avoiding sending samples to the medical laboratories. It has been extensively explored for diagnosing and monitoring patients’ diseases and health conditions with the assistance of development in biochemistry and microfluidics. Microfluidic paper-based analytical devices （μPADs） have gained dramatic popularity in POCT because of their simplicity， user-friendly， fast and accurate result reading and low cost. Several μPADs have been successfully commercialized and received excellent feedback during the past several decades. This review briefly discusses the main types of μPADs， preparation methods and their detection principles， followed by a few representative examples. The future perspectives of the development in μPADs are also provided.

Key words： point-of-care testing; microfluidic paper-based analytical devices; sensor; personalized medical treatment; portable diagnostic equipment

CLC number： TP212                     Document code： A DOI： 10.3969/j.issn.1007-7146.2025.01.001

摘 要：即時(shí)檢驗(yàn)（POCT）是指在患者現(xiàn)場(chǎng)或附近進(jìn)行的一類診斷測(cè)試（也稱為床邊測(cè)試），能夠通過使用便攜式診斷設(shè)備在短時(shí)間內(nèi)獲得準(zhǔn)確的結(jié)果，避免將樣本送往醫(yī)學(xué)實(shí)驗(yàn)室。（剩余38669字）