射血分?jǐn)?shù)超常的心力衰竭的研究進(jìn)展
【中圖分類號】R541.62【文獻(xiàn)標(biāo)識碼】A DOI：10.12114/j.issn.1007-9572.2024.0307
【Abstract】More and more studies have proved that heart failure with supra-normal ejection fraction（HFsnEF） isanewheartfailurephenotypewithdiferentcharacteristics，butitsstudyisstillintheexploratorystageathomeandbroad Thecriticalvalueofsupernomaljectionfraction（snLVEF）isstllontroversial，butmoststudiesdefineitasleftvtricular ejection fraction>65 % ；the proportion of elderly and female patientswith HFsnEFis higher，with lower natriuretic peptide valuesandsmalerleftventricles，andvalvulardisease，arhthmia，andhypertensiveheartdiseasearethemaincausesofheart failure；andtherelationshipbetween HFsnEFandmortalityhasagender-dependentnature，posiblyduetotheprevalenceof coronarymicrovasculardisorders inelderlywomen，coupledwithsmallheartsizeandhighsympatheticexcitability，making them morelikelytosuffercardiovascularevents；thecurrentdiagnosisandtreatmentofHFsnEFstllfollowstheHFpEFapproachBy combingtheliterature，thispapersystematicallydiscusss theresearchprogressofHFsnEF，withaviewtoprovidingaeference for the in-depth study of HFsnEF.
【Key Words】Heartfailure；Heartfailure with supra-normal ejectionfraction；Ejectionfraction；Sympathetic nervous system；Review
心力衰竭是不同病因引起的一組臨床綜合征，其病理生理機(jī)制存在差異，包含3個要素：（1）心臟結(jié)構(gòu)和/或功能異常；（2）心力衰竭的癥狀和/或體征；（3）腦鈉肽水平升高和/或肺部或全身瘀血的客觀證據(jù)。（剩余13964字）